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Article

Pathogen specific cytokine release reveals an effect of TLR2 Arg753Gln during Candida sepsis in humans.

Cytokine - 1 Mar 2008

Woehrle Tobias, Du Weidong, Goetz Achim, Hsu Hsin-Yun, Joos Thomas O, Weiss Manfred, Bauer Ute, Brueckner Uwe B, Marion Schneider E

Abstract excerpt

Toll-like receptors (TLRs) are crucial pattern-recognition receptors (PRRs) for activation of innate and adapted immunity. TLR2 heterodimerizes with TLR1 or TLR6 to recognize multiple pathogen-associated molecular patterns (PAMPs) of fungi, Gram-positive pathogens, and mycobacteria. Receptor acti...

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Source

Identifiers

PMID: 18249133
DOI: 10.1016/j.cyto.2007.12.006

Genes

TLR2
TLR1
TLR6
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18249133-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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