Article
Short arm of chromosome 11 and sporadic Alzheimer's disease: catalase and cathepsin D gene polymorphisms.
Neuroscience letters - 27 Feb 2008
Capurso Cristiano, Solfrizzi Vincenzo, D'Introno Alessia, Colacicco Anna M, Capurso Sabrina A, Bifaro Luigia, Menga Roberta, Santamato Andrea, Seripa Davide, Pilotto Alberto, Capurso Antonio, Panza Francesco
Abstract excerpt
Catalase (CAT) -262 C/T promoter (rs1001179), cathepsin D (CTSD) exon 2 (rs17571), and apolipoprotein E (APOE) gene polymorphisms were studied in 242 patients with sporadic Alzheimer's disease (AD) and 421 unrelated age-, sex-, and ethnically matched control subjects from Apulia (Southern Italy). No statistically significant differences in CAT rs1001179 and CTSD rs17571 genotype and allele distribution between AD...
Read the complete abstract on PubMed