Article
Virtual-karyotyping with SNP microarrays in morphologically challenging renal cell neoplasms: a practical and useful diagnostic modality.
The American journal of surgical pathology - 1 Sept 2009
Kim Hyun-Jung, Shen Steven S, Ayala Alberto G, Ro Jae Y, Truong Luan D, Alvarez Karla, Bridge Julia A, Gatalica Zoran, Hagenkord Jill M, Gonzalez-Berjon José M, Monzon Federico A
Abstract excerpt
Approximately 7 % of renal cell tumors are reported to be "unclassified" renal cell carcinoma (RCC) under the current (morphology-based) classification. Genetic lesions characteristic for RCC subtypes can be identified by virtual karyotyping with single nucleotide polymorphisms (SNP) microarrays. In this study, we examined whether virtual karyotypes could be used to better classify a cohort of morphologically...
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