Article
Impact of leptin and leptin-receptor gene polymorphisms on serum lipids in Japanese obese children.
Acta paediatrica (Oslo, Norway : 1992) - 1 Aug 2010
Okada T, Ohzeki T, Nakagawa Y, Sugihara S, Arisaka O
Abstract excerpt
AIM: Leptin is one of the factors affecting serum lipid profile. We investigated the association between serum lipids and leptin/leptin receptor (LEPR) gene polymorphisms in obese Japanese children. METHODS: One hundred and thirty-six obese children (99 males and 37 females, relative weight over than 20%) from 5 to 17 years of age were recruited from 10 institutes. Four known polymorphisms in leptin gene [(+19)A...
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