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Article

Polymorphisms in the leptin receptor gene, body composition and fat distribution in overweight and obese women.

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 May 2001

Wauters M, Mertens I, Chagnon M, Rankinen T, Considine R V, Chagnon Y C, Van Gaal L F, Bouchard C

Abstract excerpt

OBJECTIVE: Leptin is an adipocyte-secreted hormone involved in body weight regulation, acting through the leptin receptor, localised centrally in the hypothalamus as well as peripherally, amongst others on adipose tissue. The aim of this study was to evaluate whether polymorphisms in the leptin receptor (LEPR) gene were related to obesity and body fat distribution phenotypes, such as waist and hip circumferences...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11360155
DOI: 10.1038/sj.ijo.0801609

Genes

LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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