Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LEPR gene polymorphism and plasma soluble leptin receptor levels are associated with polycystic ovary syndrome in Han Chinese women.

Personalized medicine - 1 Jul 2017

Tu Xiaoyu, Yu Chuanning, Gao Minzhi, Zhang Yu, Zhang Zhaofeng, He Yaqiong, Yao Lihua, Du Jing, Sun Yun, Sun Zhaogui

Abstract excerpt

AIM: To investigate the association of LEPR polymorphisms and plasma leptin and soluble leptin receptor (sOB-R) levels with polycystic ovary syndrome (PCOS) in Chinese women. PATIENTS & METHODS: LEPR Lys109Arg (rs1137100) and Gln223Arg (rs1137101) polymorphisms of PCOS patients and the controls were genotyped. Plasma leptin and sOB-R levels of two groups were measured. RESULTS: The genotypic distributions of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People
Share to Case-Control Studies
Share to China
Share to Ethnicity
Share to Gene Expression
Share to Leptin
Share to Polycystic Ovary Syndrome
Share to Receptors, Leptin

Source

Identifiers

PMID: 29749830
DOI: 10.2217/pme-2017-0016

Genes

LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LEPR gene polymorphism and plasma soluble leptin receptor levels are associated with polycystic ovary syndrome in Han Chinese women.PMID 29749830Read ↗

Relationship between leptin receptor and polycystic ovary syndrome.Semantic proximity Read ↗

Association between leptin receptor polymorphisms and polycystic ovary syndrome risk: a meta-analysis based on 11 studies.Semantic proximity Read ↗

Association of leptin G2548A and leptin receptor Q223R polymorphisms and their serum levels with infertility and recurrent pregnancy loss in Iranian women with polycystic ovary syndrome.Semantic proximity Read ↗

LEP rs7799039 and LEPR rs1137101 gene variants are not associated with clinical features in patients with metabolic syndrome in the Turkish population.Semantic proximity Read ↗

Variations in the Obesity Gene "LEPR" Contribute to Risk of Type 2 Diabetes Mellitus: Evidence from a Meta-Analysis.Semantic proximity Read ↗

Association of leptin receptor gene polymorphisms and essential hypertension in a Chinese population.Semantic proximity Read ↗

Leptin receptor rs1137101 polymorphism and altered leptin-sOb-R axis contribute to type 2 diabetes risk in Gujarat population.Semantic proximity Read ↗

Synergistic effect of LEP and LEPR gene polymorphism on body mass index in a Chinese population.Semantic proximity Read ↗

[Meta-analysis on the relationship between leptin receptor Gln223Arg and Pro1019Pro gene polymorphism and obesity in the Chinese population].Semantic proximity Read ↗

Contrasting association of Leptin receptor polymorphisms and haplotypes with polycystic ovary syndrome in Bahraini and Tunisian women: a case-control study.Semantic proximity Read ↗

Genome-wide association study identifies polymorphisms in LEPR as determinants of plasma soluble leptin receptor levels.Semantic proximity Read ↗

Impact of leptin and leptin-receptor gene polymorphisms on serum lipids in Japanese obese children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.