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Article

Evaluation of the relationship between polymorphisms in CYP2C19 and the pharmacokinetics of omeprazole, pantoprazole and rabeprazole.

Pharmacogenomics - 1 Jan 2014

Román Manuel, Ochoa Dolores, Sánchez-Rojas Sergio Daniel, Talegón Maria, Prieto-Pérez Rocio, Rivas Ângela, Abad-Santos Francisco, Cabaleiro Teresa

Abstract excerpt

AIM: To evaluate the possible association between polymorphisms in CYP2C19 and the pharmacokinetics of omeprazole, rabeprazole and pantoprazole. MATERIALS & METHODS: 151 healthy volunteers were evaluated for polymorphisms in the CYP2C19 gene using real-time polymerase chain reaction. Plasma concentrations were measured using high-performance liquid chromatography coupled to mass spectrometry. RESULTS: Carriers of...

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Identifiers

PMID: 25495411
DOI: 10.2217/pgs.14.141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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