CYP2C19 gene polymorphism in Ningxia.

doi:10.1007/s43440-023-00473-5

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CYP2C19 gene polymorphism in Ningxia.

Pharmacological reports : PR - 1 Jun 2023

Yang Zhen, Xie Yunqian, Zhang Daya, Zou Yan, Li Ximei, Chen Runxiang, Zhang Xiaodong, Chen Shiju, Bai Feihu

Abstract excerpt

BACKGROUND: Poor metabolizer (PM) status of CYP2C19 can be a predisposing factor for developing gastric cancer in H. pylori-infected patients. It is unclear whether PM status of CYP2C19 can also be a potential factor for H.pylori infection in healthy people. METHODS: We used high-throughput sequencing to detect single nucleotide polymorphisms (SNPs) at just three loci, rs4244285 (CYP2C19*2), rs4986893 (CYP2C19*3)...

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PMID: 36913175
DOI: 10.1007/s43440-023-00473-5

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