Article
Modifying effects of IL-6 polymorphisms on body size-associated breast cancer risk.
Obesity (Silver Spring, Md.) - 1 Feb 2008
Slattery Martha L, Curtin Karen, Sweeney Carol, Wolff Roger K, Baumgartner Richard N, Baumgartner Kathy B, Giuliano Anna R, Byers Tim
Abstract excerpt
OBJECTIVE: The association between obesity and breast cancer risk is complex. We examined whether the association between body size and breast cancer risk is modified by interleukin-6 (IL6) genotype. METHODS AND PROCEDURES: Five polymorphisms in the IL-6 gene (rs1800797/-596A>G, rs1800796/-572G>C, rs1800795/-174G>C, rs2069832/IVS2G>A, and rs2069849 exon 5 C>T) were studied. We investigated IL6 genotypes and...
