Article
Nasal abnormalities in cystic fibrosis mice independent of infection and inflammation.
American journal of respiratory cell and molecular biology - 1 Jul 2008
Hilliard Tom N, Zhu Jie, Farley Ray, Escudero-Garcia Sara, Wainwright Brandon J, Jeffery Peter K, Griesenbach Uta, Bush Andrew, Davies Jane C, Alton Eric W F W
Abstract excerpt
It is not known whether the progressive airway changes in cystic fibrosis (CF) are all secondary to infection and inflammation. The CF mouse nose shares electrophysiologic and cellular properties with human CF airway epithelium. In the present work, we tested the hypothesis that structural abnorm...
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