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Article

Cystic fibrosis mouse models.

American journal of respiratory cell and molecular biology - 1 Jan 2007

Guilbault Claudine, Saeed Zienab, Downey Gregory P, Radzioch Danuta

Abstract excerpt

Animal models of cystic fibrosis (CF) are powerful tools that enable the study of the mechanisms and complexities of human disease. Murine models have several intrinsic advantages compared with other animal models, including lower cost, maintenance, and rapid reproduction rate. Mice can be easily genetically manipulated by making transgenic or knockout mice, or by backcrossing to well-defined inbred strains in a...

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Identifiers

PMID: 16888286
DOI: 10.1165/rcmb.2006-0184TR

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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