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Article

Uncovering Cystic Fibrosis Carrier: Insights From a Heterozygous CFTR-F508del Rabbit Model.

International forum of allergy & rhinology - 1 Aug 2026

Cho Do-Yeon, McFeely Alexis E, Skinner Daniel, Zhang Shaoyan, Hedvat Justin, Ping-Ay Weslee, Beswick Daniel M, Turner Justin H, Woodworth Bradford A, Xu Jie

Abstract excerpt

BACKGROUND: Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disorder frequently associated with impaired mucociliary clearance and bacterial infection. Individuals carrying a single cystic fibrosis transmembrane conductance regulator (CFTR) mutation exhibit partial CFTR dysfunction and are increasingly recognized as being at risk for CRS; however, the sinonasal phenotype and host-pathogen...

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Source

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Identifiers

PMID: 41758072
DOI: 10.1002/alr.70128
PMCID: PMC13432446

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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