Article
FGFR3 mutations and a normal CK20 staining pattern define low-grade noninvasive urothelial bladder tumours.
European urology - 1 Sept 2007
van Oers Johanna M M, Wild Peter J, Burger Maximilian, Denzinger Stefan, Stoehr Robert, Rosskopf Elke, Hofstaedter Ferdinand, Steyerberg Ewout W, Klinkhammer-Schalke Monika, Zwarthoff Ellen C, van der Kwast Theodorus H, Hartmann Arndt
Abstract excerpt
OBJECTIVES: Molecular markers superior to conventional clinicopathologic parameters are needed to predict disease courses in bladder cancer patients. In this study, we investigated four markers (Ki-67, TP53, CK20, FGFR3) in primary urothelial bladder tumours and compared them with traditional pathologic features. METHODS: Tissue microarrays were used to analyse CK20, TP53, and Ki-67 expression...
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