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Article

Flagellin of enteropathogenic Escherichia coli stimulates interleukin-8 production in T84 cells.

Infection and immunity - 1 Apr 2003

Zhou Xin, Girón Jorge A, Torres Alfredo G, Crawford J Adam, Negrete Erasmo, Vogel Stefanie N, Kaper James B

Abstract excerpt

The type III secretion system (TTSS) of enteropathogenic Escherichia coli (EPEC) has been associated with the ability of these bacteria to induce secretion of proinflammatory cytokines, including interleukin-8 (IL-8), in cultured epithelial cells. However, the identity of the effector molecule directly involved in this event is unknown. In this study, we determined that the native flagellar filament and its...

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Identifiers

PMID: 12654834
DOI: 10.1128/IAI.71.4.2120-2129.2003
PMCID: PMC152053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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