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Article

Central Role for B Lymphocytes and CD4 <sup>+</sup> T Cells in Immunity to Infection by the Attaching and Effacing Pathogen <i>Citrobacter rodentium</i>

21 Aug 2003

Abstract excerpt

Citrobacter rodentium, an attaching-effacing bacterial pathogen, establishes an acute infection of the murine colonic epithelium and induces a mild colitis in immunocompetent mice. This study describes the role of T-cell subsets and B lymphocytes in immunity to C. rodentium. C57Bl/6 mice orally infected with C. rodentium resolved infection within 3 to 4 weeks. Conversely, systemic and colonic tissues of RAG1(-/-)...

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Identifiers

PMID: 12933850
DOI: 10.1128/iai.71.9.5077-5086.2003

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