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Article

Distinct Roles of the Antiapoptotic Effectors NleB and NleF from Enteropathogenic Escherichia coli.

Infection and immunity - 1 Apr 2017

Pollock Georgina L, Oates Clare V L, Giogha Cristina, Wong Fok Lung Tania, Ong Sze Ying, Pearson Jaclyn S, Hartland Elizabeth L

Abstract excerpt

During infection, enteropathogenic Escherichia coli (EPEC) translocates effector proteins directly into the cytosol of infected enterocytes using a type III secretion system (T3SS). Once inside the host cell, these effector proteins subvert various immune signaling pathways, including death receptor-induced apoptosis. One such effector protein is the non-locus of enterocyte effacement (LEE)-encoded effector...

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Identifiers

PMID: 28138023
DOI: 10.1128/IAI.01071-16
PMCID: PMC5364307

Genes

FAS
FADD
RIPK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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