Heterozygosity for interleukin-18 -607 A/C polymorphism is associated with risk for colorectal cancer.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Heterozygosity for interleukin-18 -607 A/C polymorphism is associated with risk for colorectal cancer.

Anticancer research - 1 Jan 2000

Nikiteas Nikolaos, Yannopoulos Athanasios, Chatzitheofylaktou Agapi, Tsigris Christos

Abstract excerpt

BACKGROUND: The possible contribution of interleukin-18 (IL-18) -607 A/C polymorphism towards the development of colorectal cancer was investigated. PATIENTS AND METHODS: DNA samples of 84 patients with colorectal cancer (adenocarcinomas) and 89 healthy controls were examined by allele-specific polymerase chain reaction followed by electrophoretic analysis. The resulting allele and genotype frequencies of...

Topics

Adenocarcinoma
Alleles
Case-Control Studies
Colorectal Neoplasms
Genetic Predisposition to Disease
Genotype
Heterozygote
Humans
Interleukin-18
Neoplasm Staging
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 18225542

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics