Article
Significant association between interleukin-17A polymorphism and colorectal cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2014
Omrane Inés, Marrakchi Raja, Baroudi Olfa, Mezlini Amel, Ayari Hager, Medimegh Imen, Stambouli Nejla, Kourda Nadia, Bouzaienne Hassen, Uhrhammer Nancy, Bougatef Karim, Bignon Yves-Jean Jean, Benammar-Elgaaied Amel
Abstract excerpt
Interleukin (IL) 17A is an inflammatory cytokine expressed by Th 17 cells and plays a role in tissue inflammation by inducing release of proinflammatory and neutrophil-mobilizing cytokines. We have investigated the association between colorectal cancer and polymorphisms of IL17A (rs2275913. G197A). The study was performed in 241 subjects (102 with colorectal cancer and 139 healthy controls). Genotypes were...
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