Article
The interleukin-18 -607A/C polymorphism is not associated with risk for oral cancer.
Anticancer research - 1 Jan 2000
Vairaktaris Eleftherios, Serefoglou Zoe Charalambus, Yapijakis Christos, Agapi Chatzitheofylaktou, Vassiliou Stavros, Nkenke Emeka, Antonis Vylliotis, Sofia Spyridonidou, Neukam Friedrich Wilhelm, Patsouris Efstratios
Abstract excerpt
BACKGROUND: The purpose of the present study was to investigate the association of angiogenesis-inhibitor interleukin-18 (IL-18) with risk for oral cancer, with regard to the recently found contribution of cytokines to carcinogenesis. PATIENTS AND METHODS: The -607A/C polymorphism in the promoter region of the IL-18 gene, which affects transcription, was studied in 149 patients with oral squamous cell carcinoma...
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