Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial release factor in yeast: interplay of functional domains.

Current genetics - 1 Mar 2008

Kutner Jan, Towpik Joanna, Ginalski Krzysztof, Boguta Magdalena

Abstract excerpt

The MRF1 gene encodes the only class I release factor found in Saccharomyces cerevisiae mitochondria, mRF1. The previously isolated point mutation mrf1-13 caused respiratory deficiency due to inhibition of mitochondrial translation. In this study, we have isolated second-site suppressors of mrf1-13. Among over 200 respiratory positive suppressor colonies, ten nuclear dominant suppressors had a new mutation in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Western
Share to Gene Expression Regulation, Fungal
Share to Mitochondria

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mitochondrial Proteins

Share to Peptide Termination Factors

Share to Ribosomes

Share to Saccharomyces cerevisiae Proteins

Share to Suppression, Genetic

Source

Identifiers

PMID: 18224323
DOI: 10.1007/s00294-008-0177-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial release factor in yeast: interplay of functional domains.PMID 18224323Read ↗

The yeast nuclear gene MRF1 encodes a mitochondrial peptide chain release factor and cures several mitochondrial RNA splicing defects.Semantic proximity Read ↗

Single point mutations in domain II of the yeast mitochondrial release factor mRF-1 affect ribosome binding.Semantic proximity Read ↗

Temperature-sensitive mutation in yeast mitochondrial ribosome recycling factor (RRF).Semantic proximity Read ↗

Mutation in a new gene MAF1 affects tRNA suppressor efficiency in Saccharomyces cerevisiae.Semantic proximity Read ↗

Up-regulation of tRNA biosynthesis affects translational readthrough in maf1-delta mutant of Saccharomyces cerevisiae.Semantic proximity Read ↗

Temperature sensitivity caused by mutant release factor 1 is suppressed by mutations that affect 16S rRNA maturation.Semantic proximity Read ↗

Mitochondrial diseases: Yeast as a model for the study of suppressors.Semantic proximity Read ↗

Evolution and diversification of the organellar release factor family.Semantic proximity Read ↗

The YrdC protein--a putative ribosome maturation factor.Semantic proximity Read ↗

Subcellular relocalization of a long-chain fatty acid CoA ligase by a suppressor mutation alleviates a respiration deficiency in Saccharomyces cerevisiae.Semantic proximity Read ↗

Mmf1p, a novel yeast mitochondrial protein conserved throughout evolution and involved in maintenance of the mitochondrial genome.Semantic proximity Read ↗

Translational readthrough of a termination codon in the yeast mitochondrial mRNA VAR1 as a result of mutation in the release factor mRF1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.