Subcellular relocalization of a long-chain fatty acid CoA ligase by a suppressor mutation alleviates a respiration deficiency in Saccharomyces cerevisiae.

doi:10.1002/j.1460-2075.1994.tb06890.x

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Article

Subcellular relocalization of a long-chain fatty acid CoA ligase by a suppressor mutation alleviates a respiration deficiency in Saccharomyces cerevisiae.

The EMBO journal - 1 Dec 1994

Harington A, Schwarz E, Slonimski P P, Herbert C J

Abstract excerpt

We have isolated an extragenic suppressor, FAM1-1, which is able to restore respiratory growth to a deletion of the CEM1 gene (mitochondrial beta-keto-acyl synthase). The sequence of the suppressor strongly suggests that it encodes a long-chain fatty acid CoA ligase (fatty-acyl-CoA synthetase). W...

Topics

3-Oxoacyl-(Acyl-Carrier-Protein) Synthase
Alleles
Amino Acid Sequence
Animals
Biological Transport
Chromosomes, Fungal
Cloning, Molecular
Coenzyme A Ligases
Fungal Proteins
Genes, Suppressor
Mitochondria

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Oxygen Consumption

Phenotype

Repressor Proteins

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Sequence Homology, Amino Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 7988550
DOI: 10.1002/j.1460-2075.1994.tb06890.x
PMCID: PMC395515

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7988550-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Subcellular relocalization of a long-chain fatty acid CoA ligase by a suppressor mutation alleviates a respiration deficiency in Saccharomyces cerevisiae.PMID 7988550Read ↗

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