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Article

Single point mutations in domain II of the yeast mitochondrial release factor mRF-1 affect ribosome binding.

Nucleic acids research - 25 Nov 1993

Pel H J, Rep M, Dubbink H J, Grivell L A

Abstract excerpt

We have recently described two yeast strains that are mutated in the MRF1 gene encoding the mitochondrial release factor mRF-1. Both mutants provoke gene-specific defects in mitochondrial translational termination. In the present study we report the cloning, sequencing, as well as an analysis of residual activities of both mutant mrf1 alleles. Each allele specifies a different single amino acid substitution...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8265342
DOI: 10.1093/nar/21.23.5308
PMCID: PMC310563

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Source receipt: pubmed, retrieved 7 Sept 2026.

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