Article
Influence of lansoprazole and rabeprazole on mycophenolic acid pharmacokinetics one year after renal transplantation.
Therapeutic drug monitoring - 1 Feb 2008
Miura Masatomo, Satoh Shigeru, Inoue Kazuyuki, Kagaya Hideaki, Saito Mitsuru, Suzuki Toshio, Habuchi Tomonori
Abstract excerpt
Peptic ulcer disease is a common complication after organ transplantation, and long-term administration of antiulcer agents is needed in many renal transplant recipients. Although several drug interactions with mycophenolic acid (MPA), the active metabolite of the prodrug mycophenolate mofetil (MMF), have been reported, little is known about the interaction between MPA and proton pump inhibitors (PPIs). The...
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