Article
Correlation of IMPDH1 gene polymorphisms with subclinical acute rejection and mycophenolic acid exposure parameters on day 28 after renal transplantation.
Basic & clinical pharmacology & toxicology - 1 Aug 2010
Kagaya Hideaki, Miura Masatomo, Saito Mitsuru, Habuchi Tomonori, Satoh Shigeru
Abstract excerpt
The risk of acute rejection in patients with higher exposure to mycophenolic acid (MPA), the active metabolite of mycophenolate mofetil (MMF), might be due to inosine 5'-monophosphate dehydrogenase (IMPDH) polymorphisms. The correlations with subclinical acute rejection, IMPDH1 polymorphisms and...
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