Article
Influence of UGT1A7 and UGT1A9 intronic I399 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients.
Therapeutic drug monitoring - 1 Jun 2007
Inoue Kazuyuki, Miura Masatomo, Satoh Shigeru, Kagaya Hideaki, Saito Mitsuru, Habuchi Tomonori, Suzuki Toshio
Abstract excerpt
UGT1A7 and UGT1A9 are uridine diphosphate-glucuronosyltransferase isoforms involved in the glucuronidation of mycophenolic acid (MPA). The aim of this study was to elucidate MPA pharmacokinetics in UGT1A7 and UGT1A9 intronic I399 genotypes in Japanese adult renal transplant recipients. Eighty rec...
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