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Article

Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the Women's Health Initiative Observational Study.

Diabetes - 1 Apr 2008

Hsu Yi-Hsiang, Niu Tianhua, Song Yiqing, Tinker Lesley, Kuller Lewis H, Liu Simin

Abstract excerpt

OBJECTIVE: Mitochondrial uncoupling proteins (UCPs) are involved in body weight regulation and glucose homeostasis. Genetic variants in the UCP2-UCP3 gene cluster, located on chromosome 11q13, may play a significant role in the development of type 2 diabetes. RESEARCH DESIGN AND METHODS: We conducted a comprehensive assessment of common single nucleotide polymorphisms (SNPs) at the 70-kb UCP2-UCP3 gene cluster in...

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Source

Identifiers

PMID: 18223008
DOI: 10.2337/db07-1269

Genes

UCP3
UCP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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