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Article

Molecular screening of genetic defects with RNA-SSCP analysis: the PKU and cystinuria model.

Molecular and cellular probes - 1 Jun 1995

Giannattasio S, Bisceglia L, Lattanzio P, Grifa A, Dianzani I, Gasparini P, Marra E

Abstract excerpt

RNA single-strand conformation polymorphism (rSSCP) is a recently developed method for detecting genetic defects. This technique requires DNA amplification with a polymerase chain reaction making use of one T7 promoter-containing primer. Amplification products are subsequently transcribed in vitro and the labelled transcripts are analysed for single-strand conformation changes. rSSCP has been applied to mutation...

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Identifiers

PMID: 7477014
DOI: 10.1006/mcpr.1995.0032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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