Article
[PCR-SSCP--rapid and easy detection of DNA-sequence changes].
Human cell - 1 Jun 1992
Hayashi K
Abstract excerpt
PCR-SSCP analysis is a rapid, simple and sensitive technique for detection of various mutations, including single nucleotide substitutions, insertions and deletions, in PCR-amplified DNA fragments. Here I review, the principle and sensitivity of the technique, and also show how this technique has been used in clinical and basic medical sciences.
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