[PCR-SSCP--rapid and easy detection of DNA-sequence changes].

Abstract excerpt

PCR-SSCP analysis is a rapid, simple and sensitive technique for detection of various mutations, including single nucleotide substitutions, insertions and deletions, in PCR-amplified DNA fragments. Here I review, the principle and sensitivity of the technique, and also show how this technique has...

Topics

• Base Sequence
• DNA, Single-Stranded
• Humans
• Mutation
• Neoplasms
• Nucleic Acid Conformation
• Polymerase Chain Reaction
• Polymorphism, Genetic