Article
CaSm (LSm-1) overexpression in lung cancer and mesothelioma is required for transformed phenotypes.
American journal of respiratory cell and molecular biology - 1 Jun 2008
Watson Patricia M, Miller Scott W, Fraig Mostafa, Cole David J, Watson Dennis K, Boylan Alice M
Abstract excerpt
CaSm (cancer-associated Sm-like) was originally identified based on elevated expression in pancreatic cancer and in several cancer-derived cell lines. It encodes a 133-amino acid protein that contains two Sm motifs found in the common snRNP proteins and the LSm (like-Sm) family of proteins. Lung tumors and mesotheliomas express high levels of CaSm mRNA and protein compared with adjacent nontumor and normal lung...
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