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Article

RBM10 promotes transformation-associated processes in small cell lung cancer and is directly regulated by RBM5.

PloS one - 1 Jan 2017

Loiselle Julie J, Roy Justin G, Sutherland Leslie C

Abstract excerpt

Lung cancers are the leading cause of cancer-related deaths worldwide, with small cell lung cancer (SCLC) being the most aggressive type. At the time of diagnosis, SCLC has usually already metastasized, and an astonishing 95% of patients eventually succumb to the disease. This highlights the need for more effective SCLC screening and treatment options. Interestingly, the earliest and most frequent genetic...

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Topics

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Share to Cell Cycle Proteins
Share to Cell Proliferation
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Complementary

Share to RNA-Binding Proteins

Share to Sequence Analysis, RNA

Share to Small Cell Lung Carcinoma

Share to Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 28662214
DOI: 10.1371/journal.pone.0180258
PMCID: PMC5491171

Genes

RBM10
RBM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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