Cathepsin G, a leukocyte protease, activates coagulation factor VIII.

Abstract excerpt

Neutrophils and monocytes express cathepsin G and can also bind to activated platelets, thus they can be localized to the site of active coagulation. Previous studies have suggested that cathepsin G inactivated coagulation factor VIII (FVIII) and was thus anticoagulant. But other studies have indicated procoagulant functions for cathepsin G in activation of coagulation factor V or activation of platelets among...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Blood Coagulation
• Share to Cathepsins
• Share to Disulfides