Article
Evolutionary selection against change in many Alu repeat sequences interspersed through primate genomes.
Proceedings of the National Academy of Sciences of the United States of America - 21 Jun 1994
Britten R J
Abstract excerpt
Mutations have been examined in the 1500 interspersed Alu repeats of human DNA that have been sequenced and are nearly full length. There is a set of particular changes at certain positions that rarely occur (termed suppressed changes) compared to the average of identical changes of identical nuc...
Topics
- Animals
- Base Sequence
- Biological Evolution
- Gene Expression Regulation
- Genes, Regulator
- Genome
- Hominidae
- Humans
- Models, Genetic
- Molecular Sequence Data
- Mutation
- Primates
- Promoter Regions, Genetic
- Repetitive Sequences, Nucleic Acid
- Selection, Genetic
- Suppression, Genetic
- Time