Article
Motifome comparison between modern human, Neanderthal and Denisovan.
BMC genomics - 18 Jun 2018
Cserhati Matyas F, Mooter Mary-Ellen, Peterson Lauren, Wicks Benjamin, Xiao Peng, Pauley Mark, Guda Chittibabu
Abstract excerpt
BACKGROUND: The availability of the genomes of two archaic humans, Neanderthal and Denisovan, and that of modern humans provides researchers an opportunity to investigate genetic differences between these three subspecies on a genome-wide scale. Here we describe an algorithm that predicts statistically significant motifs based on the difference between a given motif's actual and expected distributions. The...
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