Article
Association between genetic polymorphisms of MMP8 and the risk of steroid-induced osteonecrosis of the femoral head in the population of northern China.
Medicine - 1 Sept 2016
Du Jieli, Jin Tianbo, Cao Yuju, Chen Junyu, Guo Yongchang, Sun Mingqi, Li Jian, Zhang Xiyang, Wang Guoqiang, Wang Jianzhong
Abstract excerpt
BACKGROUND: Steroid-induced osteonecrosis of the femoral head (ONFH) is the most common clinical nontraumatic ONFH. Once ONFH occurs, it seriously reduces patients' quality of life. The matrix metalloproteinase/tissue inhibitor of metalloproteinase (MMP/TIMP) system was found to play a significant role in the development of ONFH. The aim of this study was to identify the associations between 7 genes selected from...
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