Polymorphism in the matrix metalloproteinase-2 gene promoter is associated with cervical neoplasm risk in Mexican women.

doi:10.1007/s10528-007-9136-4

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Article

Polymorphism in the matrix metalloproteinase-2 gene promoter is associated with cervical neoplasm risk in Mexican women.

Biochemical genetics - 1 Apr 2008

Baltazar-Rodriguez Luz M, Anaya-Ventura Aristoteles, Andrade-Soto Maricela, Monrroy-Guizar Elisa A, Bautista-Lam Jose R, Jonguitud-Olguin Gregorio, Cepeda-Lopez Friedman R, Centeno-Aguilar Veronica A, Gonzalez-Hernandez Nelida A, Soriano-Hernández Alejandro D, Ramirez-Flores Mario, Lugo-Trampe Angel, Rodriguez-Sanchez Iram P, Newton-Sanchez Oscar A, Delgado-Enciso Ivan

Abstract excerpt

Matrix metalloproteinase-2 (MMP-2) is an enzyme with proteolytic activity on matrix proteins, and previous studies have revealed a strong association between the MMP-2 -1306C-->T polymorphism and the risk of several types of cancer. Our study looked at whether this polymorphism contributed to the development of cervical neoplasia by analyzing 54 patients with invasive squamous cell cervical cancer, 100 patients...

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PMID: 18210196
DOI: 10.1007/s10528-007-9136-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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