Article
Matrix metalloproteinase-1 and -9 promoter polymorphisms and endometrial carcinoma risk in a Japanese population.
Journal of the Society for Gynecologic Investigation - 1 Oct 2006
Sugimoto Makoto, Yoshida Shigeki, Kennedy Stephen, Deguchi Masashi, Ohara Noriyuki, Maruo Takeshi
Abstract excerpt
OBJECTIVE: The matrix metalloproteinases (MMPs) are a family of zinc-dependent proteases that degrade all the components of the extracellular matrix (ECM). Several studies have demonstrated association between MMP gene polymorphisms and various cancers. The object of this study was to investigate whether the MMP-1 and MMP-9 gene promoter polymorphisms are associated with endometrial carcinomas in a Japanese...
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