Matrix metalloproteinase-2 promoter polymorphism is associated with breast cancer in a Mexican population.

doi:10.1159/000108282

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Article

Matrix metalloproteinase-2 promoter polymorphism is associated with breast cancer in a Mexican population.

Gynecologic and obstetric investigation - 1 Jan 2008

Delgado-Enciso Iván, Cepeda-Lopez Friedman R, Monrroy-Guizar Elisa A, Bautista-Lam Jose R, Andrade-Soto Maricela, Jonguitud-Olguin Gregorio, Rodriguez-Hernandez Alejandrina, Anaya-Ventura Aristoteles, Baltazar-Rodriguez Luz M, Orozco-Ruiz Martha, Soriano-Hernandez Alejandro D, Rodriguez-Sanchez Iram P, Lugo-Trampe Angel, Espinoza-Gomez Francisco, Michel-Peregrina Martha L

Abstract excerpt

BACKGROUND: Matrix metalloproteinase-2 (MMP-2) is an enzyme with proteolytic activity on matrix proteins, particularly basement membrane constituents. A single nucleotide polymorphism C>T transition at -1306 displayed a strong association with several cancers. Our study investigated whether or not the MMP-2 -1306C>T polymorphism contributed to the development of breast cancer (BC) in a Mexican population....

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PMID: 17851253
DOI: 10.1159/000108282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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