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Environmental-Genetic Interactions in the Pathogenesis of Parkinson's Disease

18 Sept 2012

Abstract excerpt

To date, numerous case-control studies have shown the complexity of the pathogenesis of Parkinson's disease (PD). In terms of genetic factors, several susceptibility genes are known to contribute to the development of PD, including α-synuclein (SNCA), leucine-rich repeat kinase 2 (LRRK2), and glucocerebrosidase (GBA). In addition, numerous recent epidemiological studies have shown that several environmental...

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PMID: 23055790
DOI: 10.5607/en.2012.21.3.123

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