Article
Haplotypes of the fibrinogen gene and cerebral small vessel disease: the Rotterdam scan study.
Journal of neurology, neurosurgery, and psychiatry - 1 Jul 2008
van Oijen M, Cheung E Y L, Geluk C E M, Hofman A, Koudstaal P J, Breteler M M B, de Maat M P
Abstract excerpt
OBJECTIVE: Fibrinogen levels and fibrinogen clot structure have been implicated in the pathogenesis of vascular disease. We examined fibrinogen levels and variation in fibrinogen genes (fibrinogen gamma (FGG), alpha (FGA) and beta (FGB)), which have been associated with fibrin clot structure and fibrinogen levels, in relation to cerebral small vessel disease (SVD). METHODS AND RESULTS: This study was performed as...
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