Article
Genetic Polymorphisms Associated with Thrombotic Disease Comparison of Two Territories: Myocardial Infarction and Ischemic Stroke.
Disease markers - 1 Jan 2019
Isordia-Salas Irma, Martínez-Marino Manuel, Alberti-Minutti Paolo, Ricardo-Moreno María Tania, Castro-Calvo Ricardo, Santiago-Germán David, Alvarado-Moreno José Antonio, Calleja-Carreño Cristian, Hernández-Juárez Jesús, Leaños-Miranda Alfredo, Majluf-Cruz Abraham
Abstract excerpt
BACKGROUND AND PURPOSE: The thrombin-activatable fibrinolysis inhibitor (TAFI) is an important inhibitor of fibrinolysis and plays a critical role in the pathogenesis of arterial thrombosis; genetic polymorphisms of the TAFI gene affect its activity and increase the risk of thrombosis. Moreover, studies in young patients are still scarce. The aim was to examine the contribution of the Thr325Ile and Ala147Thr...
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