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Article

C677T mutation of methylenetetrahydrofolate reductase gene and serum homocysteine levels in Turkish patients with coronary artery disease.

Cell biochemistry and function - 1 Jan 2000

Yilmaz Hulya, Isbir Selim, Agachan Bedia, Ergen Arzu, Farsak Bora, Isbir Turgay

Abstract excerpt

Elevated levels of homocysteine is a risk factor for coronary artery disease. The C677T transition in methylenetetrahydrofolate reductase (MTHFR) is associated with increased homocysteine levels in the general population. We analysed the association between the MTHFR C677T polymorphism and serum homocysteine concentrations in patients with coronary artery disease (CAD). Allele frequencies for the 'C' (wild-type)...

Topics

Alleles
Blood Pressure
Body Mass Index
Coronary Artery Disease
Female
Genotype
Homocysteine
Humans
Male
Methylenetetrahydrofolate Reductase (NADPH2)
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation, Missense

Turkey

Source

Identifiers

PMID: 15648053
DOI: 10.1002/cbf.1206

Genes

MTHFR
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15648053-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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C677T mutation of methylenetetrahydrofolate reductase gene and serum homocysteine levels in Turkish patients with coronary artery disease.PMID 15648053Read ↗

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