The methylenetetrahydrofolate reductase gene polymorphism in Koreans with coronary artery disease.

doi:10.1016/s0167-5273(00)00431-9

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Article

The methylenetetrahydrofolate reductase gene polymorphism in Koreans with coronary artery disease.

International journal of cardiology - 1 Mar 2001

Kim C H, Hwang K Y, Choi T M, Shin W Y, Hong S Y

Abstract excerpt

Hyperhomocysteinemia is a known risk factor of cardiovascular diseases. Methylenetetrahydrofolate reductase (MTHFR), involved in folate-dependant metabolism, is associated with homocysteine levels. We studied the associations among MTHFR genotypes, coronary artery disease (CAD), and homocysteine levels in 85 patients with CAD and 152 healthy subjects. The MTHFR genotypes and plasma homocysteine levels were...

Topics

Aged
Asian People
Coronary Disease
Female
Genotype
Homocysteine
Humans
Korea
Male
Methylenetetrahydrofolate Reductase (NADPH2)
Middle Aged
Mutation
Oxidoreductases Acting on CH-NH Group Donors
Phenotype
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 11259808
DOI: 10.1016/s0167-5273(00)00431-9

Genes

MTHFR
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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