Article
Hyperhomocysteinaemia, methylenetetrahydrofolate reductase polymorphism and risk of coronary artery disease.
Annals of clinical biochemistry - 1 May 2006
Kerkeni Mohsen, Addad Faouzi, Chauffert Maryline, Myara Anne, Gerhardt Marie, Chevenne Didier, Trivin François, Farhat Mohamed Ben, Miled Abdelhedi, Maaroufi Khira
Abstract excerpt
BACKGROUND: Hyperhomocysteinaemia is an independent, graded risk factor for coronary artery disease (CAD). The methylenetetrahydrofolate reductase (MTHFR) polymorphism is associated with hyperhomcysteinaemia and may therefore influence individual susceptibility to CAD. We have investigated this risk factor in a Tunisian Arab population. METHODS: Polymerase chain reaction-restriction fragment length polymorphism...
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