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Article

Association of the methylene-tetrahydrofolate reductase gene rs1801133 C677T variant with serum homocysteine levels, and the severity of coronary artery disease.

Scientific reports - 22 Jun 2020

Bouzidi Nadia, Hassine Majed, Fodha Hajer, Ben Messaoud Mejdi, Maatouk Faouzi, Gamra Habib, Ferchichi Salima

Abstract excerpt

This study aimed to investigate whether the single nucleotide polymorphism C677T (rs1801133) of the methylene-tetrahydrofolate reductase (MTHFR) gene was associated with the risk of coronary artery disease (CAD) and circulating homocysteine (Hcy) levels in Tunisian population. 310 angiografically diagnosed CAD patients and 210 controls were enrolled in this study. The MTHFR C677T (rs1801133) polymorphism was...

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Identifiers

PMID: 32572074
DOI: 10.1038/s41598-020-66937-3
PMCID: PMC7308346

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