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Article

Targeted disruption of the galectin-3 gene results in decreased susceptibility to NNK-induced lung tumorigenesis: an oligonucleotide microarray study.

Journal of cancer research and clinical oncology - 1 Jul 2008

Abdel-Aziz Hekmat Osman, Murai Yoshihiro, Takasaki Ichiro, Tabuchi Yoshiaki, Zheng Hua-chuan, Nomoto Kazuhiro, Takahashi Hiroyuki, Tsuneyama Koichi, Kato Ichiro, Hsu Daniel K, Liu Fu-tong, Hiraga Koichi, Takano Yasuo

Abstract excerpt

PURPOSE: Galectin-3, a beta-galactoside-binding animal lectin is a multifunctional protein, which regulates cell growth, cell adhesion, cell proliferation, angiogenesis, and apoptosis, and in turn contributes to tumorigenesis and metastasis. The aim of this study was to clarify the role or related mechanisms of galectin-3 in lung carcinogenesis. METHODS: We administrated...

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PMID: 18204863
DOI: 10.1007/s00432-007-0345-3

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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