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Article

Genome-wide significance for dense SNP and resequencing data.

Genetic epidemiology - 1 Feb 2008

Hoggart Clive J, Clark Taane G, De Iorio Maria, Whittaker John C, Balding David J

Abstract excerpt

The problem of multiple testing is an important aspect of genome-wide association studies, and will become more important as marker densities increase. The problem has been tackled with permutation and false discovery rate procedures and with Bayes factors, but each approach faces difficulties that we briefly review. In the current context of multiple studies on different genotyping platforms, we argue for the...

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PMID: 18200594
DOI: 10.1002/gepi.20292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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