Article

The multiple testing burden in sequencing-based disease studies of global populations

2016-05-13

Abstract excerpt

Genome-wide association studies (GWAS) of common disease have been hugely successful in implicating loci that modify disease risk. The bulk of these associations have proven robust and reproducible, in part due to community adoption of statistical criteria for claiming significant genotype-phenotype associations. Currently, studies of common disease are rapidly shifting towards the use of sequencing technologies....

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Literature Corpus work: d0bb72d6-c22a-5f51-82ba-46702788be23
DOI: 10.1101/053264

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