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Article

Singleton SNPs in the human genome and implications for genome-wide association studies.

European journal of human genetics : EJHG - 1 Apr 2008

Ke Xiayi, Taylor Martin S, Cardon Lon R

Abstract excerpt

The human genome is estimated to contain one single nucleotide polymorphism (SNP) every 300 base pairs. The presence of LD between SNP markers can be used to save genotyping cost via appropriate SNP tagging strategies, whereas absence or low level of LD between markers generally increase genotyping cost. It is quite common that a large proportion of tagging SNPs in a tagging scheme often turn out to be singleton...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18197193
DOI: 10.1038/sj.ejhg.5201987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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