Article
Single nucleotide polymorphisms (SNPs) that map to gaps in the human SNP map.
Nucleic acids research - 15 Aug 2003
Tsui Circe, Coleman Laura E, Griffith Jacqulyn L, Bennett E Andrew, Goodson Summer G, Scott Jason D, Pittard W Stephen, Devine Scott E
Abstract excerpt
An international effort is underway to generate a comprehensive haplotype map (HapMap) of the human genome represented by an estimated 300,000 to 1 million 'tag' single nucleotide polymorphisms (SNPs). Our analysis indicates that the current human SNP map is not sufficiently dense to support the HapMap project. For example, 24.6% of the genome currently lacks SNPs at the minimal density and spacing that would be...
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