Article
Association between matrix metalloproteinase 9 promoter polymorphisms and Behçet's disease.
Human immunology - 1 Jul 2010
Lee Yun Jong, Kang Seong Wook, Baek Han Joo, Choi Hyo Jin, Bae Young Deok, Kang Eun Ha, Lee Eun Young, Lee Eun Bong, Song Yeong Wook
Abstract excerpt
Matrix metalloproteinase (MMP)-9 expression is reported to be upregulated in several primary vasculitides. The -1562C>T and -91 [CA](n) repeat polymorphisms can affect MMP-9 promoter activity. We investigated the distributions of these functional polymorphisms in 122 patients with Behçet's disease (BD) and in 122 gender- and age-matched healthy controls. Plasma levels of MMP-9 were analyzed. The frequency of "L"...
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